Substituted N-phenylpyrazine-2-carboxamides: Synthesis and antimycobacterial evaluation

Abstrakt

Twelve newly prepared pyrazinecarboxamides were evaluated for their antimycobacterial activity against four different Mycobacterium strains and at the Tuberculosis Antimicrobial Acquisition and Coordinating Facility (TAACF, USA) program.

Klíčová slova

• pyrazinecarboxamide synthesis
• in vitro antimycobacterial screening
• lipophilicity
• SAR