Matrix-free thin-layer chromatography/laser desorption ionization mass spectrometry for facile separation and identification of medicinal alkaloids

Abstrakt

Thin-layer chromatography (TLC) combined with laser desorption/ionization mass spectrometry (LDI-MS) was used for analysis of a pharmaceutically important class of isoquinoline alkaloids associated with bactericidal, fungicidal, insecticidal and antiviral activities.

Klíčová slova

• assisted laser-desorption
• MALDI-TOF-MS
• berberine
• induction
• apoptosis
• TLC