Determination of lipophilicity of novel potential antituberculotic agents using HPLC on monolithic stationary phase and theoretical calculations

Abstract

Lipophilic parameters of two series of newly synthesized antituberculotic compounds were determined using both experimental method (RP-HPLC) and the theoretical calculations [12th meeting on recent developments in pharmaceutical analysis (RDPA 2007); SEP 23-26 2007; Elba, Italy]

Keywords

• lipophilicity
• monolithic column
• HPLC
• partition coefficient
• chemical software