Sensitive chiral high-performance liquid chromatographic determination of anthelmintic flubendazole and its phase I metabolites in blood plasma using UV photodiode-array and fluorescence detection; Application to pharmacokinetic studies in sheep

Abstract

New chiral bioanalytical HPLC method and results from in vivo ovine pharmacokinetics of flubendazole and its phase I metabolites

Keywords

• flubendazole
• metabolites
• chiral HPLC-PDA-fluorescence
• pharmacokinetics in sheep