Radiolabelling of glucose-Tyr3-octreotate with 125-I and analysis of its metabolites in rats: comparison with radiolabelled DOTA-Tyr(3)-octreotate

Abstract

The procedures for the radioiodination of the glucose-Tyr(3)-octreotate and radiolabelling of DOTA-Tyr(3)-octreotate with In-125, Lu-177 and I-125 were compared and the metabolism in rats was analysed

Keywords

• somatostatin peptide analogues
• radiolabelling
• radiochemical purity
• metabolism