Publication at First Faculty of Medicine, Faculty of Physical Education and Sport |
2012
Abstract
Aortic stenosis is the third most common cardiovascular disease and the most commonly operataed valve disease in developed countries. Progressive valve calcification leading to significant flow obstruction is the main pathogenetic feature.
Dysregulation of the systemic calcium-phosphate metabolism with low vitamin D level is a possible risk factor of aortic stenosis even in patients with preserved renal function. This hypothesis deserves further clinical and experimental study.