Abstract
Although tumours of the thymus are rare, they are common among neoplasms of the anterior superior mediastinum. They usually exhibit indolent behaviour, but do have the capacity to invade surrouding structures.
Their metastatic potential is low. Paraneoplastic complications including autoimmune disorders (fre quently myastenia, cytopenia) or combined immunodeficiency are of clinical significance.
Here we report two case reports of thymoma patients associated with secondary immunodeficiency known as Good's syndrom. The first case exhibited as symptomatic combinated immunodeficiency with opral lichen planus.
Thymoma findings was accidental. Severity of immunodeficiency required long-term intravenous immunoglobulines supplementations, even after complete surgical resection.
On the other hand, the second case manifested by signs of advanced local tumor growth. Antibiotic prophylaxis was selected as immunodeficiency treatment.