Abstract
The review deals with some drugs newly available in Czech Republic and related therapeutic procedures used in the treatment of periodontal and mucosal diseases. For topical chemical inhibition of the dental plaque are dedicated octenidine, and combination of chlorhexidine with eugenol.
As adjuvant chemotherapeutics in the treatment of periodontitis serve systems for antimicrobial photodynamic therapy based on the use of photosensitizers, namely toluidine blue O and methylen blue. Saturated alcohol docosanol serves in topical therapy of labial herpes.
Capsaicine is selective agonist of vanilloid receptore TRPV of sensitive nerves. Qutenza has been recently used for topical treatment of neuropatic pain.
It could be potentially very useful agent in the treatment of some forms of atypical facial pain. Irradiation of salivary glands results in association with its dosis in the damage of various grade of the glandular parenchyma associated with postirradiative hyposialia.
Cytoprotective prodrug amifostine is recommended for the protection of the glandular parenchyma against adverse effects of therapeutic irradiation in the region of the head and neck. Spectrum of therapeutic agents useful in the treatment of periodontal and mucosal diseases raises permanently.
Efficacy of their application is connected with sufficient information of proffesionals and correct and early diagnosis of the disease, as well.