Other transition metal-mediated cyclizations leading to cyclopentenones

Abstract

In spite of all the efforts expended in the quest for new non-metallic methodologies for the synthesis of cyclopentenones, transition metal-mediated strategies remain the most common approach. Apart from the Pauson-Khand reaction and related transformations, numerous other approaches have also emerged through the years.

These approaches are discussed in this chapter.

Keywords

• Pauson-Khand reaction
• intramolecular 1,5-C-H insertions
• Nazarov reaction
• intramolecular Wittig type reactions