Abstract
In our case report we present a middle-aged woman with saddle-nose, long-lasting chronic rhinitis and later attending complains such as fever, cough and weakness, accompanied by increased inflammatory markers and bilateral pulmonary infiltrates on the chest X-ray. The pulmonary findings were resistant to various types of antibiotic therapy.
The patient was recommended to the admission at our Pulmonary clinic to solve that diagnostic problem. Saddle-nose was a remarkable sign which caused in association with the detailed personal medical history, laboratory tests and some examination results, our urgent suspicion of Wegener's granulomatosis.
The diagnosis was confirmed particularly by upper and lower air-ways histological findings and positivity of ANCA-antibodies, as well as the good answer on the immunosuppressive therapy.