C-terminal Acidic Cluster Is Involved in Ca2+-induced Regulation of Human Transient Receptor Potential Ankyrin 1 Channel

Abstract

The C-terminal acidic cluster is involved in the Ca2+ induced potentiation and inactivation of TRPA1. Identification of the Ca2+ dependent domain is important for understanding the role of TRPA1 in chemical nociception

Keywords

• TRPA1
• transient receptor potential ankyrin