A role of hybrid imaging methods in the detection of occult pyogenous musculoskeletal inflammations in patients in septic state A role of hybrid imaging methods in the detection of occult pyogenous musculoskeletal inflammations in patients in septic state A role of hybrid imaging methods in the detection of occult pyogenous musculoskeletal inflammations in patients in septic state
Abstract
Aim. To asses a role and frequency of indications of hybrid imaging methods in the detection of occult pyogenous musculoskeletal inflammation as a cause of the septic state of unknown origin.
Method. The retrospective evaluation of the hybrid imaging indicated due a sepsis of unknown origin during three years was performed.
All procedures of 18F-FDG-PET/CT and the SPECT/CT using labeled leucocytes were enrolled into the assessment. Results. 27 procedures of 18F-FDG-PET/CT were performed due to the searching of the cause in cases of the sepsis of unknown origin; the spondylodiscitis was found in 6 cases, pyogenous arthritis in 3 cases, muscular abscesses in 2 cases and 4 cases of pyogenous infection of implanted joint prosthesis.
Muskuloskeletal inflammations formed 55,5% of all findings. 16 procedures of SPECT/CT were performed, 10 using 99mTc-labeled antigranulocyte antibodies, and 6 using 99mTc-HMPAO labeled leukocytes. In 2 cases, the acute spondylodiscitis was found, one case of chronic spondylitis and one case of soft tissue abscesses due to the infection of endoprosthesis were found.
Muskuloskeletal inflammations formed 25% of all findings. Conclusion.
During the period of the parallel use of PET/CT and SPECT/CT in detection of occult infection, the majority of procedures were performed using 18F-FDG- PET/CT, offering multiple advantages over leukocyte imaging.