Abstract
Heritability of anxiety disorders is the least of all psychiatric diseases – only 20 to 40%. Environmental factors, especially the psychotraumatizing ones, are deciding.
Although series of genetic association studies in anxiety disorders have already been performed, their results are typically negative, inconsistent, or non-replicated. On the present day, practically no gene can be considered as a causative one in the etiopathogenesis of anxiety disorders.
A basically new knowlege can be attained by whole-genome association studies and genetic analyses of endophenotypes in the future. It will be useful in our finding of modern biological therapies in anxiety disorders.