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Pharmacogenomical prediction of the effect of taxifen in the treatment of hormonal-dependent post-menopausal women with breast cancer

Publication at First Faculty of Medicine |
2010

Abstract

The initial stages of breast cancer are well treatable nowadays, provided the therapy is appropriate. Hormonal therapy is one of the basic therapeutic modalities for the hormone- dependent breast cancer.

In this artikle, we offer our preliminary results of several factors influencing the effect of tamoxifen, extended with new, yet unexplored factor – polymorfism of MDR-1.