The restructuring of dopamine receptor subtype gene transcripts in c-fos KO mice

Abstract

The aim of the study was to evaluate the changes of dopaminergic system together with acetylcholinesterase (AChE) in c-fos disruption (KO). Main interactions in WT were inter-regional, CNS of KO underwent an extensive restructuring comprising intraregional interactions in the frontal cortex, hypothalamus, and cerebellum.

Keywords

• c-fos
• Dopamine receptors
• Cerebral cortex
• Cerebellum
• Hypothalamus
• Striatum
• Hippocampus
• long-term-memory
• sex-differences
• nervous-system
• mouse striatum
• null mutation
• expression
• nucleus
• protooncogene
• variability
• cocaine