Abstract
Anaphylaxis in pregnancy is a relatively rare reaction but it can lead to serious maternal and fetal impairment. In published cases of severe anaphylaxis in pregnancy there were even more severe disabilities in the fetus than the mother.
Development of anaphylaxis is usually unpredictable, the first symptoms are sometimes atypical and only local, but can move quickly in a generalized impairment of the whole organism. Whatever they are mediated by IgE antibodies (right anaphylaxis), or are caused on another basis (anaphylactoid reactions), the clinical picture is similar.
It should be kept in mind that even clinically inconspicuous initial symptoms may progress into serious and life-threatening state. Any omission and delay in diagnosis and treatment of anaphylaxis can lead to fatal end.
A successful outcome is largely dependent on experience and timeliness of medical intervention. Because this topic is mentioned in contemporary literature rather rarely, this review therefore summarizes the issue of anaphylaxis in pregnancy in terms of pathophysiology, clinical course, diagnosis and treatment.
Whatever they are mediated by IgE antibodies (right anaphylaxis), or are caused on another basis (anaphylactoid reactions), the clinical picture is similar. It should be kept in mind that even clinically inconspicuous initial symptoms may progress into serious and life-threatening state.
Any omission and delay in diagnosis and treatment of anaphylaxis can lead to fatal end. A successful outcome is largely dependent on experience and timeliness of medical intervention.
Because this topic is mentioned in contemporary literature rather rarely, this review therefore summarizes the issue of anaphylaxis in pregnancy in terms of pathophysiology, clinical course, diagnosis and treatment.