Immune-Glutamatergic Dysfunction as a Central Mechanism of the Autism Spectrum Disorders

Abstract

Cellular and molecular dysfunction associated with autism spectrum disorders is not known; there is evidence of involvement of the glutamatergic neurotransmission with enhancement of excitatory receptor function by pro-inflammatory immune cytokines as the underlying mechanism.

Keywords

• autism spectrum disorders
• excitotoxicity
• fluoride
• glutamatergic neurotransmission
• inflamation
• mercury
• microglia
• cytokones