Abstract
History of melanosome research can be divided into 3 stages: 1. Melanosome Research in pre-Seiji era; 2) Melanosome Research in Seijis era (1961-1982); 3.
Melanosome Research in post Seiji era. Key findings in ultrastructural, histochemical and biochemical studies of melanosomes have been reviewed.
Significant contribution of Charles University scientists to the world pool of knowledge in this research area has been underlined.