The reproducibility of measurements of differential renal function in paediatric Tc-99m-MAG3 renography
Abstract
The aims of the study were to establish the reproducibility of estimates of differential renal function obtained using the software supplied by different vendors, assess the effects of age, glomerular filtration rate and degree of asymmetry of renal function on reproducibility and ascertain whether the software gives the same estimates of differential renal function. Reproducibility found was good in the majority of children.
An appreciable minority showed poor reproducibility which could impact clinical decision making. It is essential that these studies be identified.
This can be done by processing each renogram several times, ideally using different methods. Children with poorer reproducibility tended to be less than 6 months old or to have low glomerular filtration rate.