Role of Common Canalicular Transporter Gene Variations in Aetiology of Idiopathic Gallstones in Childhood

Abstract

Common variations in genes encoding canalicular transporters known to contribute to genetic predisposition to cholesterol gallstones in adulthood do not contribute specifically to the aetiology of paediatric idiopathic gallstones.

Keywords

• cholelithiasis
• polymorphism
• ABCB11
• ABCG8
• salt export pump
• disease
• mdr3
• cholelithiasis
• cholestasis
• association
• deficiency
• cirrhosis
• liver