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Diffusion-weighted Image and the Prediction of Brain Venous Thrombosis Development on Magnetic Resonance - Two Case Reports

Publication at First Faculty of Medicine, Second Faculty of Medicine |
2011

Abstract

We present two cases with diagnoses of cerebral venous thrombosis with extensive pathological changes supporting ischemia on conventional MR imaging (MRI). MR angiography disclosed thrombosis of the vein of Galen and cerebral sinuses.

The findings were different on diffusion-weighted imaging (DWI) and on ADC maps. The first case exhibited high signal intensity on DWI and intermediate-to-low signal intensity on ADC (apparent diffusion coefficient) maps in the affected area.

This indicated cytotoxic oedema and ischemic lesions. The second case showed intermediate-to-low signal intensity on DWI and high signal intensity on ADC maps.

This indicated vasogenic oedema. The severe clinical status of both patients necessitated admittance to the intensive care unit and anticoagulation therapy.