Exhaled leukotrienes and bronchial responsiveness to methacholine in patients with seasonal allergic rhinitis

Abstract

Allergic rhinitis and bronchial asthma can coexist and affect each other.To investigate the relationship between the postseasonal increase in the concentration of leukotriene (LT) B4 and LTE4 in exhaled breath condensate (EBC) and bronchial responsiveness to methacholine (BRM) in patients with seasonal allergic rhinitis (SAR).

Keywords

• chromatography/mass spectrometry analysis
• condensate cysteinyl leukotrienes
• breath condensate
• airway hyperresponsiveness
• asthmatic-children
• childhood asthma
• nitric-oxide
• 8-isoprostane
• inflammation
• challenge