Recognition of Galactose-Deficient O-Glycans in the Hinge Region of IgA1 by N-Acetylgalactosamine-Specific Snail Lectins: A Comparative Binding Study

Abstract

These studies provide insight into lectin recognition of the Gal-deficient IgA1 hinge region and lay the groundwork for the development of reliable diagnostic tools for IgAN.

Keywords

• Henoch-Schonlein purpura
• flight mass-spectromectry
• human serum IgA 1
• nephropathy patients