Changing spectrum of Candida spp. as causative agent of invasive candidiasis and candidemia – status quo in Europe, Czech and Slovak republics

Abstract

After fluconazole introduction, besides a slow decrease of incidence of candidiasis, a lower appearance of Candida albicans infections and relatively higher incidence of infections caused by non-albicans Candida species was seen. This fact should influence the decision what antimycotic use both for prophylaxis and treatment.

We present a review of epidemiologic data concerning incidence of candidemia mainly in Europe and Czech and Slovak republics, with emphasizing changing spectrum of Candida spp.

Keywords

• invasive candidiasis
• candidemia
• Candida albicans
• non-albicans Candida
• changing spectrum