The effect of rapid and depot testosterone and estradiol on spatial performance in water maze

Abstract

We evaluated spatial performance (escape latency, overall improvement, and time in the quadrant after platform removal) of the rats in a spatial water maze. Animals receiving exogenous sex steroids showed higher plasma concentrations of the particular hormones.

Experimental groups improved during the acquisition spatial trials in the water maze.

Keywords

• Water maze
• Spatial performance
• Testosterone
• Estradiol
• Hippocampus
• Rats