Activation of adenosine A(3) receptors supports hematopoiesis-stimulating effects of granulocyte colony-stimulating factor in sublethally irradiated mice

Abstract

IB-MECA given to sublethally irradiated mice concomitantly with G-CSF significantly enhanced GM-CFC and BFU-E numbers compared to controls irradiated only or irradiated and treated only wihr G-CSF or IB-MECA.

Keywords

• ionising radiation
• hematopoiesis
• adenosine A3