Publication at First Faculty of Medicine |
2012
Abstract
Resistant hypertension is diagnosed when a therapeutic plan entailing implementation of lifestyle measures and prescription of at least three drugs, including a diuretic, in adequate doses, has failed to lower SBP and DBP to goal. It remains a major clinical problem in spite of the availability of many effective antihypertensive agents.
Among the several possible causes of resistant hypertension, those attributable to drugs or abuse of substances are the majority, likely more than 58%.