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Mitochondrial Dysfunction

Publication at First Faculty of Medicine, Third Faculty of Medicine |
2009

Abstract

Cell-mediated immunity (CMI) response of healthy humans and cancer (Ca) patients to specific tumor antigen and nonspecific (LDV-lactate dehydrogenase virus) antigen, and of acute myocardial infarction (AMI) and schizophrenia (Sch) patients to nonspecific antigen was investigated. Large differences of CMI response of healthy humans in comparison with Ca, AMI, Sch patients were found.

CMI response to antigens displays transferred information about cells under immune surveillance. LDV disturbs the oxidative energy production system.

We assume that CMI response to LDV antigen monitors pathological states of mitochondrial energy production which results in disturbances of electromagnetic activity of living cells