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Thromboembolism, coagulation and atherothrombosis

Publication at First Faculty of Medicine |
2011

Abstract

The epidemiological and clinical relations between venous thromboembolism and increased incidence of cardiovascular diseases are intensively studied at present. The classic concept of atherosclerosis indicate a pivotal role of inflammation in the development and progression of this disease.

Atherothrombosis is a disease specific for „a modern“ population and is the most common disease, which significantly increases mortality and impaires prognosis of the patients. This is a generalized process affecting large and medium size arteries in a human body.

Experimental data indicate that platelets and the coagulation system are important factors of both atherogenesis and atherothrombosis.