Fenofibrate Metabolism in the Cynomolgus Monkey using Ultraperformance Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics

Abstract

In the present study, the metabolism of fenofibrate was investigated in cynomolgus monkeys by ultraperformance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOFMS)-based metabolomics.

Keywords

• ACTIVATED-RECEPTOR-ALPHA
• RAT SKELETAL-MUSCLE
• CLOFIBRIC ACID
• PEROXISOME PROLIFERATORS
• SPECIES-DIFFERENCES
• HEPATIC PEROXISOME
• GEMFIBROZIL
• HEPATOCARCINOGENESIS
• DISPOSITION
• TOXICITY