Abstract
Hypertension accompanying renal disease is among the most common secondary hypertensions. Chronic renal diseases affect approximately 10 % of the population.
Four percent of adult persons are expected to have concurrent chronic renal insufficiency (CRI) of varied severity and hypertension. The pathogenesis of hypertension in CRI mostly involves impaired regulation of extracellular fluid volume and imbalance between vasoconstrictive and vasodilatory agents.
The goals of treatment for hypertension in CRI are to attain a target blood pressure of less than 130/80 mm Hg, slow down the progression of chronic renal disease, interfere with pre-existent hypertensionrelated complications, and manage other risk factors of cardiovascular disease. Attainment of effective hypertension control requires a combination of several antihypertensives.