Liver, but not adipose tissue PEDF gene expression is associated with insulin resistance

Abstract

OBJECTIVE: Recent studies linked circulating pigment epithelium-derived factor (PEDF) to obesity-associated insulin resistance, but the main source of circulating PEDF is unknown. We aimed to investigate liver and adipose tissue PEDF gene expression in association with obesity and insulin resistance.

Keywords

• Pigment epithelium-derived factor
• insulin resistance
• adipose tissue
• liver