The effect of very-low-calorie diet on mRNA expression of inflammation-related genes in subcutaneous adipose tissue and peripheral monocytes of obese patients with type 2 diabetes mellitus

Abstrakt

Obese patients with and without T2DM have increased mRNA expression of chemotactic and proinflammatory factors in SCAT and expression of corresponding receptors in PM. Two weeks of VLCD significantly improved this profile in T2DM patients.

Klíčová slova

• Insulin-resistance
• chemoattractant protein-1
• macrophage infiltration
• weight-loss
• disease
• accumulation
• adipocytes
• chemokines
• resident