Unlike the controls, 55 patients with Wilson's disease were more prone to daytime napping accompanied by tiredness and excessive daytime sleepiness, cataplexy-like episodes and poor nocturnal sleep. The changes were proved by nocturnal polysomnography and multiple sleep latency tests eaximed during the day.
Patiernts with Wilson's disease often suffer from sleep disturbances regardless of the clinical form and the spectrum slerep/wake symptoms raised the suspicious that altered REM sleep functions may also be involved.