Involvement of c-Src activity in the mTOR-dependent oncogenicity of melanoma cells

Abstract

Upregulation of the mTORC1 signalling pathway in melanoma cells HBL and SK-MEL-5, as well as their malignity, could be reduced by suppression of the c-Src tyrosine kinase activity

Keywords

• c-Src
• tyrosine kinase activity
• mTORC1
• melanoma