Charles Explorer logo
🇬🇧

5-Fluorouracil-based chemotherapy for colorectal cancer and MTHFR/MTRR genotypes

Publication at First Faculty of Medicine |
2011

Abstract

We investigated the role of six genetic variants in the MTHFR and 5-methylenetetrahydrofolate-homocysteine methyltransferase reductase (MTRR) genes on the clinical outcome in 273 colorectal cancer patients who were administered a 5-FU based regimen as first-line post-operative therapy.