Abstract
Pneumoconiosis is a term for occupational respiratory disorder caused by inhalation of inorganic dusts, their macrophages ingestion and response by releasing tumor necrosis factors, and cytokines leading finally to the stimulation of fibroblasts to proliferate and produce collagen. Silicosis is caused by inhalation of crystalline silica dust, and is marked by inflammation and scarring in forms of nodular lesions especially in the upper lobes of the lungs.
Coal worker’s pneumoconiosis is caused by long-term black coal mining in deep coal mines. Both the radiological finding and symptoms are similar to silicosis; mixed ventilatory disturbance is usually present.
Asbestosis is a chronic inflammatory medical condition affecting the parenchymal tissue of the lungs. It occurs after long-term, heavy exposure to asbestos fibers, e.g. in production of insulation textile and eternit.
No causal treatment for pneumoconioses is available, therefore technical prevention is crucial to prevent the disease.