Proteomic and transcriptomic analysis of heart failure due to volume overload in a rat aortocaval fistula model provides support for new potential therapeutic targets - monoamine oxidase A and transglutaminase 2
2011
Abstract
Changes in gene and protein expression in rat model of volume overload-induced heart failure were studied at RNAlevel and by proteomic approaches. Identified changes support the role of the enzymes monoamine oxidase A and transglutaminase 2 as new potential therapeutic targets.