Neuroprotective effect of nicotine against kainic acid excitotoxicity is associated with alpha-bungarotoxin insensitive receptors subtype of nAChRs

Abstract

Nicotine administration influences alpha-bungarotoxin insensitive receptors and repeated administration is capable to protect against toxicity caused by kainic acid in hippocampal area.

Keywords

• nicotine
• kainic acid
• hippocampus
• seizure
• Fluoro-Jade B
• alpha-bungarotoxin
• insensitive receptors