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Calcifying Pseudoneoplasms of the Neural Axis. Report of Three Cases

Publication at First Faculty of Medicine, Third Faculty of Medicine |
2011

Abstract

Calcifying pseudoneoplasms of the neural axis (CAPNONA) are rare lesions that have been reported in both intra/extra-axial locations intracranially, and in extra-axial locations in the spinal region. Central loss of signal on T1/T2-weighted images with enhancement following contrast administration is most commonly observed on magnetic resonance imaging, however, the histopathological composition of CAPNONA is diverse which may be reflected in the imaging findings.

We present three cases of CAPNONA detected by MRI and confirmed by histological evaluation, and the largest review of the MRI characteristics of these lesions to date.