Molecular cytogenetic analysis of 11q13.2 breakpoints in three patients with acute myeloid leukemia.

Abstract

Chromosomal area 11q13 is one of rare recurent breakpoints in acute myeloid leukemia (AML). In few cases there was identified specific alterate gene - for example NUMA1 (nuclear mitotic apparatus protein 1) or MACROD1 (MACRO domain containig 1, also known as LRP16)...

Keywords

• Chromosomal area 11q13
• rare recurent breakpoints
• acute myeloid leukemia (AML)
• specific alterate gene
• NUMA1 (nuclear mitotic apparatus protein 1)
• MACROD1 (MACRO domain containig 1)
• LRP16