A partial nontandem duplication of the MLL gene in four patients with acute myeloid leukemia.

Abstract

In this report we present unusual MLL gene rearrangements found in bone marrow cells of four patients with acute myeloid leukemia.

Keywords

• Acute myeloid leukemia (AML)
• MLL
• translocation
• complex rearrangement of the karyotype
• partial nontandem duplication (PNTD)
• FISH
• mFISH
• RT-PCR