Potentially inappropriate (risk) drugs at geriatric patients: Expert consensus for the Czech Republic 2012
2012
Abstract
Demographic population ageing and geriatrization of medicine contribute to steadily increasing drug consumption. Therefore, rational prescribing is needed for maximizing of the treatment benefit for the patient and to minimize the risk of adverse drug reactions.
Age-related physiological changes and multiple comorbid conditions typical for geriatric patients influence the therapeutic value of many drugs and change their risk/benefit ratio. Medication for which there is pharmacological evidence of increased risk of adverse drug events in frail elderly patients or for which evidence of sufficient benefit is lacking are understood as potentially inappropriate (risky) medication.