Deep brain stimulation in patients suffering from movement disorders? Stereotactic procedure and intraoperative findings

Abstract

Introduction: Deep brain stimulation (DBS) is the method of choice in the treatment of various movement disorders. Methods: Between 1998 and 2009, we performed DBS in 100 patients (F : M = 37 : 63; median 56 yrs /12-73 yrs/).

Fourteen patients suffered from essential tremor (ET), 2 from tremor of other aetiology (T), 73 from Parkinson's disease (PD), 10 from generalized (GD) and 1 from cervical (CD) dystonia. Implantation was targeted in the ventral intermedial thalamus (VIM) for ET, T and PD, subthalamic nucelus (STN) for PD and internal pallidum (GPi) for GD, CD and PD.

Intracerebral electrodes were totally implanted into 187 nuclei. We evaluated stimulation parameters, while clinical response and parameters determined the accuracy of implantation.

Keywords

• Deep brain stimulation
• Parkinson's disease
• dystonia
• tremor
• intraoperative results
• accuracy of implantation
• intraoperative complication
• subthalamic nucleus stimulation
• kinase-associated neurodegeneration
• hardware-related complications
• advanced parkinsons-disease
• thalamic nucleus
• globus-pallidus
• tremor
• experience
• surgery
• accuracy