Restless legs syndrome in Czech patients with multiple sclerosis: an epidemiological and genetic study

Abstract

Restless legs syndrome (RLS) is significantly associated with multiple sclerosis (MS), especially in patients with more severe disability. MS should be considered amongst the secondary RLS forms.

The idiopathic RLS forms do not share all the major genetic features with secondary RLS forms in patients with MS.

Keywords

• Restless legs syndrome
• multiple sclerosis
• single nucleotide polymorphism
• genetic association study
• prevalence study