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Acyclic nucleoside phosphonates as potential antineoplastic agens

Publication at First Faculty of Medicine |
2008

Abstract

Potential cytostatic drug GS-9219 is a novel lipophilic prodrug of cyprPMEDAP,in vivo releasing the active compound PMEG in a two-step process.GS-9219 has shown a substantial therapeutic potential in treatment of spontaneous non-Hodgkin's lymphoma