Abstract
Therapy of dyslipidemia is a corner stone of prevention of cardiovascular complications in high-risk patients. Best documented lipid lowering agents are statins being used as a monotherapy as well as the core of combination treatment regimens.
Fibrates, ezetimibe, niacin and (in the Czech Republic practically unavailable) resins represent other treatment options of dyslipidemia. Complex intervention of all lipid abnormalities using combination of different drug classes represents an option to accomplish further reduction of cardiovascular atherothrombotic complications.