Abstract
The monophasic action potential MAP method represents a very useful tool for an electrophysiological research in cardiology. Its importance lies in the fact that it enables the study of the action potential of myocardial cell in vivo and, therefore, the study of the dynamic relation of this potential with all the organism variables what can be particularly helpful in the case of arrhythmias.
Based on available data, the MAP probably reflects the transmembrane voltage of cells within a few millimeters of the exploring electrode. Thus MAP recordings offer the opportunity to study, in the in situ heart, a variety of electrophysiological phenomena including effects of cycle length changes and antiarrhythmic drugs on the action potentials duration.