Abstract
Both the epidemiological data and results of experimental works háve shown tight relations of the insulin resistance, type 2 diabetes mellitus (DM2), cognitive disturbances and sporadic form of Alzheimers disease. Plethora of events, standing behind these relations, is associated with an abnormal brain glucose metabolism.
Some authors call Alzheimer's disease, "type 3 diabetes mellitus". In the article, an outline is given on the mechanisms, connecting both the insulin resistance and DM2 with the cognitive disturbances or dementia.
Some new potential possibilities of the favourable influencing of the sporadic form of Alzheimers disease are also mentioned. The research in the field could help to find new biolog ical markers of the Alzheimers disease, recognition of the new treatment targets and of new preventivě and treatment modalities of this serious disorder.