Analyses of LOH and expression in healthy gland, DCIS and invasive breast cancer gland

Abstract

We confirmed that substantial part of DCIS has molecular pattern similar to invasive cancer. These molecular changes could serve as potential markers of DCIS progression to invasive cancer or they could identify subgroup of DCIS with latent invasion.

Keywords

• breast cancer
• DCIS
• LCIS
• p53
• BRCA1
• BRCA2
• Bcl-2
• VEGF